Login
Search
Search
0 Dates
2026
2025
2024
2023
2022
2021
2020
2019
2018
0 Events
CPC 2018
CPC 2019
Curso de Atualização em Medicina Cardiovascular 2019
Reunião Anual Conjunta dos Grupos de Estudo de Cirurgia Cardíaca, Doenças Valvulares e Ecocardiografia da SPC
CPC 2020
CPC 2021
CPC 2022
CPC 2023
CPC 2024
CPC 2025
CPC 2026
0 Topics
A. Basics
B. Imaging
C. Arrhythmias and Device Therapy
D. Heart Failure
E. Coronary Artery Disease, Acute Coronary Syndromes, Acute Cardiac Care
F. Valvular, Myocardial, Pericardial, Pulmonary, Congenital Heart Disease
G. Aortic Disease, Peripheral Vascular Disease, Stroke
H. Interventional Cardiology and Cardiovascular Surgery
I. Hypertension
J. Preventive Cardiology
K. Cardiovascular Disease In Special Populations
L. Cardiovascular Pharmacology
M. Cardiovascular Nursing
N. E-Cardiology / Digital Health, Public Health, Health Economics, Research Methodology
O. Basic Science
P. Other
0 Themes
01. History of Cardiology
02. Clinical Skills
03. Imaging
04. Arrhythmias, General
05. Atrial Fibrillation
06. Supraventricular Tachycardia (non-AF)
07. Syncope and Bradycardia
08. Ventricular Arrhythmias and Sudden Cardiac Death (SCD)
09. Device Therapy
10. Chronic Heart Failure
11. Acute Heart Failure
12. Coronary Artery Disease (Chronic)
13. Acute Coronary Syndromes
14. Acute Cardiac Care
15. Valvular Heart Disease
16. Infective Endocarditis
17. Myocardial Disease
18. Pericardial Disease
19. Tumors of the Heart
20. Congenital Heart Disease and Pediatric Cardiology
21. Pulmonary Circulation, Pulmonary Embolism, Right Heart Failure
22. Aortic Disease
23. Peripheral Vascular and Cerebrovascular Disease
24. Stroke
25. Interventional Cardiology
26. Cardiovascular Surgery
27. Hypertension
28. Risk Factors and Prevention
29. Rehabilitation and Sports Cardiology
30. Cardiovascular Disease in Special Populations
31. Pharmacology and Pharmacotherapy
32. Cardiovascular Nursing
33. e-Cardiology / Digital Health
34. Public Health and Health Economics
35. Research Methodology
36. Basic Science
37. Miscellanea
0 Resources
Abstract
Slides
Vídeo
Report
CLEAR FILTERS
Surgical Scores Predicting mortality in Non-Surgical Endocarditis: Unexpected Strength in Long-Term Mortality Stratification
Session:
Sessão de Posters 24 - Endocardite infeciosa: estratificação de risco, tratamento e desfechos
Speaker:
Rodrigo Neves Brandão
Congress:
CPC 2026
Topic:
F. Valvular, Myocardial, Pericardial, Pulmonary, Congenital Heart Disease
Theme:
16. Infective Endocarditis
Subtheme:
16.2 Infective Endocarditis – Epidemiology, Prognosis, Outcome
Session Type:
Posters Eletrónicos
FP Number:
---
Authors:
Rodrigo Neves Brandão; Inês Madeira Santos; Luís Cotrim; Tiago Mesquita; Inês Pereira Miranda; Filipa Gerardo; Carolina Mateus; Miguel Santos
Abstract
<p><span style="font-size:11pt"><span style="font-family:Aptos,sans-serif"><strong>Background: </strong>Risk stratification in infective endocarditis (IE) remains a major challenge, particularly among patients without surgical indication. Although several biomarkers and scores have been proposed to estimate short-term risk in IE patients, their prognostic relevance for long-term mortality is less well established. Most prognostic models applied in IE were originally developed to surgical cohorts, and their performance in patients managed conservatively is still unknown.</span></span></p> <p><span style="font-size:11pt"><span style="font-family:Aptos,sans-serif"><strong>Objectives: </strong>Assess the efficacy of four surgical prognostic scores, originally developed for a surgical population, in predicting long-term mortality in patients with IE managed conservatively.</span></span></p> <p><span style="font-size:11pt"><span style="font-family:Aptos,sans-serif"><strong>Methods: </strong>Retrospective single center analysis of patients hospitalized with IE from January 2017 until October 2025. Four scores discriminative performance for (1) a composite outcome of 6-month and 1-year mortality, (2) 6-month all-cause mortality, and (3) 1-year all-cause mortality was assessed using ROC-AUC analysis. Associations with mortality were evaluated using logistic regression, individually and in a multivariable model incorporating all scores simultaneously.</span></span></p> <p><span style="font-size:11pt"><span style="font-family:Aptos,sans-serif"><strong>Results: </strong>From a total of 183 patients, 57 were managed conservatively. For the composite outcome, logistic EuroSCORE (AUC 0.71; OR: 1.04; IC 95% [1.0,1.06]; p=0.014) and EuroSCORE II (AUC 0.70;OR: 1.06; IC 95% [1.0,1.11]; p=0.037) demonstrated the highest discriminative ability, followed by PALSUSE (AUC 0.67; OR:2.32 ; IC 95% [1.14,4.67]; p=0.019); the modified AEPEI did not reach statistical significance (AUC 0.658; OR:1.62; IC 95% [0.92, 2.82]; p=0.089). Regarding 6-month mortality, logistic EUROSCORE (AUC 0.73; OR: 1.04; IC 95% [1.01,1.07]; p=0.008), EuroSCORE II (AUC 0.72; OR: 1.07; IC 95% [1.01, 1.14]; p=0.023) and PALSUSE (AUC 0.69; OR:2.56; IC 95% [1.23,5.38]; p=0.012) were significant predictors. For 1-year mortality, PALSUSE exhibited the strongest predictive performance (AUC 0.72; OR: 2.97; IC 95% [1.33,6.63]; p=0.008), followed by logistic EUROSCORE (AUC 0.70; OR: 1.03; IC 95% [1.0,1.06]; p=0.022). In all timepoints, the modified AEPEI score showed limited discriminatory value and in multivariable model incorporating all scores only PALSUSE approached significance for 1-year mortality (p=0.05). </span></span></p> <p><span style="font-size:11pt"><span style="font-family:Aptos,sans-serif"><strong>Conclusions</strong>: In patients with IE managed without surgery, scores originally designed for surgical risk stratification-particularly logistic EUROSCORE and EUROSCORE II-demonstrated unexpectedly robust capacity to predict both «early» and late mortality, outperforming the IE-specific AEPEI model. Notably, PALSUSE emerged as a relevant score for long-term (1-year) predicted all-cause mortality. These findings suggest that in conservatively managed IE, long-term prognosis may be driven predominantly by baseline comorbidity and global physiological risk-domains better captured by surgical risk scores.</span></span></p>
Slides
Our mission: To reduce the burden of cardiovascular disease
Visit our site