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Curso de Atualização em Medicina Cardiovascular 2019
Reunião Anual Conjunta dos Grupos de Estudo de Cirurgia Cardíaca, Doenças Valvulares e Ecocardiografia da SPC
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0 Topics
A. Basics
B. Imaging
C. Arrhythmias and Device Therapy
D. Heart Failure
E. Coronary Artery Disease, Acute Coronary Syndromes, Acute Cardiac Care
F. Valvular, Myocardial, Pericardial, Pulmonary, Congenital Heart Disease
G. Aortic Disease, Peripheral Vascular Disease, Stroke
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01. History of Cardiology
02. Clinical Skills
03. Imaging
04. Arrhythmias, General
05. Atrial Fibrillation
06. Supraventricular Tachycardia (non-AF)
07. Syncope and Bradycardia
08. Ventricular Arrhythmias and Sudden Cardiac Death (SCD)
09. Device Therapy
10. Chronic Heart Failure
11. Acute Heart Failure
12. Coronary Artery Disease (Chronic)
13. Acute Coronary Syndromes
14. Acute Cardiac Care
15. Valvular Heart Disease
16. Infective Endocarditis
17. Myocardial Disease
18. Pericardial Disease
19. Tumors of the Heart
20. Congenital Heart Disease and Pediatric Cardiology
21. Pulmonary Circulation, Pulmonary Embolism, Right Heart Failure
22. Aortic Disease
23. Peripheral Vascular and Cerebrovascular Disease
24. Stroke
25. Interventional Cardiology
26. Cardiovascular Surgery
27. Hypertension
28. Risk Factors and Prevention
29. Rehabilitation and Sports Cardiology
30. Cardiovascular Disease in Special Populations
31. Pharmacology and Pharmacotherapy
32. Cardiovascular Nursing
33. e-Cardiology / Digital Health
34. Public Health and Health Economics
35. Research Methodology
36. Basic Science
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Long-Term Outcomes After TEER for Primary Mitral Regurgitation: Clinical and Echocardiographic Predictors from a 10-Year Cohort
Session:
Sessão de Posters 41 - Intervenções estruturais cardíacas e resultados
Speaker:
Francisco Lemos De Sousa
Congress:
CPC 2026
Topic:
H. Interventional Cardiology and Cardiovascular Surgery
Theme:
25. Interventional Cardiology
Subtheme:
25.3 Non-coronary Cardiac Intervention
Session Type:
Posters Eletrónicos
FP Number:
---
Authors:
Francisco Lemos Sousa; Francisca Nunes; Maria Leonor Moura; Inês Rodrigues; António Gonçalves; André Lobo; Marta Almeida; Sílvia Diaz; Gustavo Pires de Morais; Bruno Melica; Ricardo Fontes-Carvalho
Abstract
<p>Background: Transcatheter edge-to-edge repair (TEER) is guideline-endorsed for symptomatic primary mitral regurgitation (PMR) in patients at elevated surgical risk. Long-term outcomes remain variable, and robust predictors of mortality or heart-failure (HF) hospitalization after TEER are not well established.</p> <p>Methods: We conducted a retrospective single-centre cohort study including consecutive PMR patients who underwent TEER between 2015–2025. The primary endpoint was a composite of all-cause mortality or HF hospitalization. Time-to-event analyses were performed using Cox proportional hazards models. Variables with clinical relevance and/or p<0.10 in univariable analyses were entered into multivariable modelling. Hazard ratios (HRs) with 95% confidence intervals (CI) were reported.</p> <p>Results: Among 67 patients, mean age was 78±8 years; 39 (58%) were male and 41 (61%) had atrial fibrillation (AF). Moderate-or-greater tricuspid regurgitation (TR) was present in 46 (69%). During follow-up, 33 (49.3%) reached the primary endpoint. In univariable Cox analysis, baseline left-atrial (LA) volume (HR 1.006 per mL; 95% CI 1.002–1.010; p=0.008) and moderate-or-greater TR (HR 2.45; 95% CI 1.01–5.98; p=0.048) were associated with the endpoint, while AF showed a nonsignificant trend (HR 2.19; p=0.057). In the multivariable model, LA volume remained the only independent predictor (HR 1.005 per mL; 95% CI 1.000–1.010; p=0.032), whereas TR (HR 1.26; p=0.675) and AF (HR 1.37; p=0.537) were not independently associated with outcomes.</p> <p>Conclusion: In this 10-year TEER cohort, larger baseline LA volume was the only variable independently associated with the composite outcome of death or HF hospitalization in our model. These findings suggest that left-atrial enlargement may hold prognostic value after TEER for PMR, although validation in larger, adequately powered studies is required.</p> <p> </p>
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