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A. Basics
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01. History of Cardiology
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04. Arrhythmias, General
05. Atrial Fibrillation
06. Supraventricular Tachycardia (non-AF)
07. Syncope and Bradycardia
08. Ventricular Arrhythmias and Sudden Cardiac Death (SCD)
09. Device Therapy
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21. Pulmonary Circulation, Pulmonary Embolism, Right Heart Failure
22. Aortic Disease
23. Peripheral Vascular and Cerebrovascular Disease
24. Stroke
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26. Cardiovascular Surgery
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28. Risk Factors and Prevention
29. Rehabilitation and Sports Cardiology
30. Cardiovascular Disease in Special Populations
31. Pharmacology and Pharmacotherapy
32. Cardiovascular Nursing
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Caregiver Burden in HeartMate 3: A Single-Center Observational Study
Session:
Sessão de Posters 50 - Terapêuticas avançadas na insuficiência cardíaca e em populações especiais
Speaker:
Inês Coutinho Dos Santos
Congress:
CPC 2026
Topic:
D. Heart Failure
Theme:
10. Chronic Heart Failure
Subtheme:
10.2 Chronic Heart Failure – Epidemiology, Prognosis, Outcome
Session Type:
Posters Eletrónicos
FP Number:
---
Authors:
Inês Coutinho dos Santos; André Moniz Garcia; Cátia Sampaio; Márcia Presume; Ana Rita Bello; Sérgio Maltês; Bruno Rocha; Catarina Brízido; Christopher Strong; Marta Marques; Carlos Aguiar
Abstract
<p style="text-align:justify"><strong>Introduction</strong>: Caregivers (CG) of patients with advanced heart failure (AHF) supported by durable left ventricular assist devices (LVAD) are essential for therapy eligibility and long-term success. However, the substantial physical and psychosocial distress associated with LVAD management and emergency care are often overlooked, potentially compromising CG well-being, caregiving capacity, patient quality of life and treatment adherence.</p> <p style="text-align:justify"><strong>Objectives</strong>: To describe the burden experienced by the primary CG of patients under LVAD with HeartMate 3™ (HM3).</p> <p style="text-align:justify"><strong>Methods</strong>: This cross-sectional observational study included all patients on HM3 support under follow-up at a single center in 2025. Patients who were on HM3 support for less then 3 months and those recently hospitalized were excluded. The primary CG was identified as the unpaid person providing most of patient’s support. Caregiver burden (CGB) was assess using the Portuguese version of the 22-item Zarit Burden Interview (ZBI) scale. Descriptive and inferential statistical analyses were performed.</p> <p style="text-align:justify"><strong>Results</strong>: Twelve male patients on HM3 for a mean of 31.0 months were included (mean age 61.2 years). Most had AHF of ischemic etiology (58.3%) and were supported as bridge to transplantation (41.7%) or to candidacy (25.0%), and most were in NYHA class II (83.3%). All their CG were female and corresponded to patients’ spouses/partners. Most were older than 50 years (83.3%) and still professionally active (58.3%). The mean ZBI score was 19.2±9.9 (range 3-35) as proposed by the original author, or 41.2±9.9 (range 22-57), according to the Portuguese version by Sequeira, 2010. The most burdensome item related to the CG’s perception of the patient’s perceived dependence on them as CG. According to the cut-offs validated for the Portuguese version, 75.0% of CG had no burden, while 25.0% exhibited some degree of CGB (16.7% mild, 8.3% severe). Among the assessed domains, the presence of CGB was associated with significantly higher scores in the impact of caregiving subdomain (p=0.012), as well as personal strain (p=0.012) and role strain (p=0.024). No significant associations in CGB were observed with NYHA class, INTERMACS profile, LVAD strategy, CG age group or employment status.</p> <p style="text-align:justify"><strong>Conclusion</strong>: In this cohort, CGB was present in one in four CG of AHF patients supported by HM3. These findings underline the importance of structured and systematic CGB assessment as part of standard HM3 care, to enable early identification of at-risk CG and implementation of tailored supportive interventions as needed.</p>
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