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Curso de Atualização em Medicina Cardiovascular 2019
Reunião Anual Conjunta dos Grupos de Estudo de Cirurgia Cardíaca, Doenças Valvulares e Ecocardiografia da SPC
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A. Basics
B. Imaging
C. Arrhythmias and Device Therapy
D. Heart Failure
E. Coronary Artery Disease, Acute Coronary Syndromes, Acute Cardiac Care
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01. History of Cardiology
02. Clinical Skills
03. Imaging
04. Arrhythmias, General
05. Atrial Fibrillation
06. Supraventricular Tachycardia (non-AF)
07. Syncope and Bradycardia
08. Ventricular Arrhythmias and Sudden Cardiac Death (SCD)
09. Device Therapy
10. Chronic Heart Failure
11. Acute Heart Failure
12. Coronary Artery Disease (Chronic)
13. Acute Coronary Syndromes
14. Acute Cardiac Care
15. Valvular Heart Disease
16. Infective Endocarditis
17. Myocardial Disease
18. Pericardial Disease
19. Tumors of the Heart
20. Congenital Heart Disease and Pediatric Cardiology
21. Pulmonary Circulation, Pulmonary Embolism, Right Heart Failure
22. Aortic Disease
23. Peripheral Vascular and Cerebrovascular Disease
24. Stroke
25. Interventional Cardiology
26. Cardiovascular Surgery
27. Hypertension
28. Risk Factors and Prevention
29. Rehabilitation and Sports Cardiology
30. Cardiovascular Disease in Special Populations
31. Pharmacology and Pharmacotherapy
32. Cardiovascular Nursing
33. e-Cardiology / Digital Health
34. Public Health and Health Economics
35. Research Methodology
36. Basic Science
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Patient-Reported Quality of Life After Atrial Fibrillation Ablation: A Real-World Study
Session:
Sessão de Posters 25 - Resultados e recorrência após ablação de FA
Speaker:
Joana Certo Pereira
Congress:
CPC 2026
Topic:
C. Arrhythmias and Device Therapy
Theme:
05. Atrial Fibrillation
Subtheme:
05.2 Atrial Fibrillation - Epidemiology, Prognosis, Outcome
Session Type:
Posters Eletrónicos
FP Number:
---
Authors:
Joana Certo Pereira; Rita Barbosa Sousa; Francisco Moscoso Costa; Daniel A. Gomes; Gustavo Rodrigues; Daniel Matos; João Carmo; Pedro Galvão Santos; Pedro Carmo; Diogo Cavaco; Francisco Belo Morgado; Pedro Adragão
Abstract
<p><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif"><strong>Background: </strong>Patients with atrial fibrillation (AF) often experience reduced quality of life (QoL), making patient-reported outcome measures (PROMs) essential in patient-centred care. Although catheter ablation improves symptoms, PROM-based QoL outcomes remain variably reported. We assessed changes in AF-related QoL in a population submitted to AF ablation using the AF Effect on Quality-of-Life (AFEQT) questionnaire.</span></span></p> <p><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif"><strong>Methods: </strong>Consecutive patients undergoing catheter ablation for AF were invited and prospectively enrolled between May 2023 and May 2025. QoL was assessed at baseline on the day of ablation (prior to the procedure) and at 1, 3, 6, 12, 18, and 24 months post-ablation. The AFEQT questionnaire includes 20 items scored from 1 to 7 and converted to a 0–100 scale, where 0 represents severely impaired QoL and 100 represents no negative QoL impact. </span></span></p> <p><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif">We assessed the change in AFEQT overall score from baseline to follow-up. A clinically meaningful improvement was defined as a >5-point increase in the overall score. A 7-day Holter was performed at discharge to detect early recurrence (ER), and AF recurrence during follow-up was assessed using Holter or 12-lead ECG. Procedural and safety outcomes were recorded.</span></span></p> <p><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif"><strong>Results:</strong> Of 1247 patients submitted to AF ablation during this period, 204 accepted the invitation and 153 completed at least one AFEQT questionnaire at follow-up and were analysed (age 62 ± 11 years; 95 men; 43% paroxysmal AF) - Figure 1A. Of those, energy source was pulsed-field ablation in 65 patients (43%) and the majority (n = 84, 54%) underwent pulmonary vein isolation only. No major adverse events were observed until discharge. ER on the 7-day Holter occurred in 17 patients (11%). </span></span></p> <p><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif">After AF ablation, AFEQT scores increased progressively from baseline to 2-year follow-up - Figure 1B. After a mean follow-up of 14±4 months, the overall AFEQT score improved significantly (53±23 to 71±22; 95% CI 14.654–21.632; p<0.001) - Figure 1C. Most patients (n = 109, 71%) achieved a clinically meaningful QoL improvement (>5-point AFEQT increase) - Figure 1D. </span></span></p> <p><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif">AF recurrence at follow-up was observed in 28% (n=43) of the patients. Importantly, QoL also improved significantly in this subgroup (54±23 to 67±22; 95% CI 6.927–19.670; p<0.001), with 66% achieving a clinically meaningful improvement, suggesting symptomatic benefit despite intermittent arrhythmia recurrence.</span></span></p> <p><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif"><strong>Conclusion: </strong>In a real-world cohort of AF ablation patients, PROM-based AFEQT assessment showed a significant improvement in QoL over time, irrespective of recurrency status, with most patients achieving a clinically meaningful benefit and low rates of early recurrence on systematic monitoring. These findings support the routine feasibility and clinical value of integrating PROMs into post-ablation follow-up.</span></span></p>
Slides
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