Login
Search
Search
0 Dates
2025
2024
2023
2022
2021
2020
2019
2018
0 Events
CPC 2018
CPC 2019
Curso de Atualização em Medicina Cardiovascular 2019
Reunião Anual Conjunta dos Grupos de Estudo de Cirurgia Cardíaca, Doenças Valvulares e Ecocardiografia da SPC
CPC 2020
CPC 2021
CPC 2022
CPC 2023
CPC 2024
CPC 2025
0 Topics
A. Basics
B. Imaging
C. Arrhythmias and Device Therapy
D. Heart Failure
E. Coronary Artery Disease, Acute Coronary Syndromes, Acute Cardiac Care
F. Valvular, Myocardial, Pericardial, Pulmonary, Congenital Heart Disease
G. Aortic Disease, Peripheral Vascular Disease, Stroke
H. Interventional Cardiology and Cardiovascular Surgery
I. Hypertension
J. Preventive Cardiology
K. Cardiovascular Disease In Special Populations
L. Cardiovascular Pharmacology
M. Cardiovascular Nursing
N. E-Cardiology / Digital Health, Public Health, Health Economics, Research Methodology
O. Basic Science
P. Other
0 Themes
01. History of Cardiology
02. Clinical Skills
03. Imaging
04. Arrhythmias, General
05. Atrial Fibrillation
06. Supraventricular Tachycardia (non-AF)
07. Syncope and Bradycardia
08. Ventricular Arrhythmias and Sudden Cardiac Death (SCD)
09. Device Therapy
10. Chronic Heart Failure
11. Acute Heart Failure
12. Coronary Artery Disease (Chronic)
13. Acute Coronary Syndromes
14. Acute Cardiac Care
15. Valvular Heart Disease
16. Infective Endocarditis
17. Myocardial Disease
18. Pericardial Disease
19. Tumors of the Heart
20. Congenital Heart Disease and Pediatric Cardiology
21. Pulmonary Circulation, Pulmonary Embolism, Right Heart Failure
22. Aortic Disease
23. Peripheral Vascular and Cerebrovascular Disease
24. Stroke
25. Interventional Cardiology
26. Cardiovascular Surgery
27. Hypertension
28. Risk Factors and Prevention
29. Rehabilitation and Sports Cardiology
30. Cardiovascular Disease in Special Populations
31. Pharmacology and Pharmacotherapy
32. Cardiovascular Nursing
33. e-Cardiology / Digital Health
34. Public Health and Health Economics
35. Research Methodology
36. Basic Science
37. Miscellanea
0 Resources
Abstract
Slides
Vídeo
Report
CLEAR FILTERS
Echocardiographic predictors of sustained ventricular tachyarrhythmias in patients with CRT-D for primary prevention
Session:
SESSÃO DE POSTERS 52 - INSUFICIÊNCIA CARDÍACA, RESSINCRONIZAÇÃO E IMAGEM
Speaker:
Julien Lopes
Congress:
CPC 2025
Topic:
C. Arrhythmias and Device Therapy
Theme:
08. Ventricular Arrhythmias and Sudden Cardiac Death (SCD)
Subtheme:
08.7 Ventricular Arrhythmias and SCD - Other
Session Type:
Cartazes
FP Number:
---
Authors:
Julien Lopes; Inês Ferreira Neves; Francisco Cardoso; Sofia Jacinto; Hélder Santos; Guilherme Portugal; Pedro Silva Cunha; Bruno Valente; Ana Lousinha; Ana Galrinho; Rui Cruz Ferreira; Mário Martins Oliveira
Abstract
<p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Aptos,sans-serif"><strong>Introduction – </strong>Patients with heart failure and reduced left ventricular ejection fraction (LVEF) have a higher incidence of ventricular arrythmias. Considering this, current guidelines recommend CRT-D implantation in primary prevention for patients with LVEF≤35% and a QRS duration ≥150 ms with left bundle branch block after at least 3 months of optimal medical therapy. Our study aimed to identify echocardiographic predictors of ventricular arrhythmias in this patient population.</span></span></p> <p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Aptos,sans-serif"><strong>Methods – </strong>Retrospective study of all patients with CRT-D implantation in primary prevention from January 2015 to July 2023 in a tertiary centre. Only patients with a transthoracic echocardiogram performed before CRT-D implantation and another performed during a 1-year follow-up (FU) time after CRT-D implantation (excluding the first 3 months) were included. Appropriate CRT-D therapy (including shocks or Anti Tachycardia Pacing (ATP)) during follow-up was noted and patients were divided into two groups according to appropriate CRT-D therapy during FU. Echocardiographic parameters at baseline and 1-year FU were analysed between the two groups to determine their potential as predictors of ventricular arrhythmias using a logistic regression model.</span></span></p> <p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Aptos,sans-serif"><strong>Results </strong>– 91 patients (mean age 65,0 ± 13,16 years; 26,4% female) were included, with a mean FU of 4,0 ± 2,5 years. 50,5% of patients had ischemic heart disease. 14 patients (15,4%) had appropriate CRT-D therapy during follow-up. There were no statistically significant differences between groups regarding ARNI (p=0,427), ACEi/ARB (p=0,938), beta-blocker (p= 0,153), SGLT2i (p= 0,618) and mineralocorticoid antagonist therapy (p= 0,721). Echocardiographic parameters at baseline that were statistically significant between the two groups were LVEDVi (108,79±32,71 vs 132,40±40,43 ml/m2; p=0,024) and LVESVi (79,34 ± 29,18 vs 100,09 ± 41,26 ml/m2; p=0,032). Left ventricular ejection fraction was not statistically significant (28,22 ± 8,19 vs 24,64 ± 8,60 %; p= 0,139). Other echocardiographic parameters such as global longitudinal strain (p=0,757), E/E’ ratio (p= 0,576) and TAPSE (p=0,308) were also not statistically significant. At 1 year follow-up, patients had a mean improvement of 16,69 ± 28,68 mL/m2 in LVEDVi; of 19,27± 24,70 mL/m2 in LVESVi and of 10,81±10,87% in LVEF and these values were not statistically significant for the prediction of arrhythmic events (p=0,445; p=0,891; p=0,813 respectively). </span></span></p> <p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Aptos,sans-serif"><strong>Conclusion</strong> – In our cohort of patients with CRT-D in primary prevention, left ventricular end-diastolic and end-systolic volumes before CRT-D implantation were predictive of arrhythmic events. Improvement in these parameters with a CRT implantation did not improve prognosis in these patients concerning the incidence of ventricular arrhythmias.</span></span></p>
Slides
Our mission: To reduce the burden of cardiovascular disease
Visit our site