Login
Search
Search
0 Dates
2025
2024
2023
2022
2021
2020
2019
2018
0 Events
CPC 2018
CPC 2019
Curso de Atualização em Medicina Cardiovascular 2019
Reunião Anual Conjunta dos Grupos de Estudo de Cirurgia Cardíaca, Doenças Valvulares e Ecocardiografia da SPC
CPC 2020
CPC 2021
CPC 2022
CPC 2023
CPC 2024
CPC 2025
0 Topics
A. Basics
B. Imaging
C. Arrhythmias and Device Therapy
D. Heart Failure
E. Coronary Artery Disease, Acute Coronary Syndromes, Acute Cardiac Care
F. Valvular, Myocardial, Pericardial, Pulmonary, Congenital Heart Disease
G. Aortic Disease, Peripheral Vascular Disease, Stroke
H. Interventional Cardiology and Cardiovascular Surgery
I. Hypertension
J. Preventive Cardiology
K. Cardiovascular Disease In Special Populations
L. Cardiovascular Pharmacology
M. Cardiovascular Nursing
N. E-Cardiology / Digital Health, Public Health, Health Economics, Research Methodology
O. Basic Science
P. Other
0 Themes
01. History of Cardiology
02. Clinical Skills
03. Imaging
04. Arrhythmias, General
05. Atrial Fibrillation
06. Supraventricular Tachycardia (non-AF)
07. Syncope and Bradycardia
08. Ventricular Arrhythmias and Sudden Cardiac Death (SCD)
09. Device Therapy
10. Chronic Heart Failure
11. Acute Heart Failure
12. Coronary Artery Disease (Chronic)
13. Acute Coronary Syndromes
14. Acute Cardiac Care
15. Valvular Heart Disease
16. Infective Endocarditis
17. Myocardial Disease
18. Pericardial Disease
19. Tumors of the Heart
20. Congenital Heart Disease and Pediatric Cardiology
21. Pulmonary Circulation, Pulmonary Embolism, Right Heart Failure
22. Aortic Disease
23. Peripheral Vascular and Cerebrovascular Disease
24. Stroke
25. Interventional Cardiology
26. Cardiovascular Surgery
27. Hypertension
28. Risk Factors and Prevention
29. Rehabilitation and Sports Cardiology
30. Cardiovascular Disease in Special Populations
31. Pharmacology and Pharmacotherapy
32. Cardiovascular Nursing
33. e-Cardiology / Digital Health
34. Public Health and Health Economics
35. Research Methodology
36. Basic Science
37. Miscellanea
0 Resources
Abstract
Slides
Vídeo
Report
CLEAR FILTERS
Epicardial adipose tissue volume are related to subclinical atherosclerosis and major adverse cardiac events in asymptomatic subjects
Session:
SESSÃO DE COMUNICAÇÕES ORAIS 13 - FRONTEIRAS INOVADORAS NO DIAGNÓSTICO DA DOENÇA ARTERIAL CORONÁRIA E AVALIAÇÃO DE RISCO: DA IMAGEM AVANÇADA AOS RESULTADOS CLÍNICOS
Speaker:
Gonçalo Bettencourt Abreu
Congress:
CPC 2025
Topic:
J. Preventive Cardiology
Theme:
28. Risk Factors and Prevention
Subtheme:
28.2 Risk Factors and Prevention – Cardiovascular Risk Assessment
Session Type:
Comunicações Orais
FP Number:
---
Authors:
Gonçalo Bettencourt Abreu; Isabel Mendonça; Débora Sá; Francisco Sousa; Matilde Ferreira; Eva Henriques; Sónia Freitas; Mariana Rodrigues; Sofia Borges; António Drummond; Ana Célia Sousa; Roberto Palma Dos Reis
Abstract
<p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif"><strong>Introduction</strong>: Epicardial adipose tissue (EAT) volume is an <span style="color:#040c28">imaging biomarker to detect individuals with a higher risk of coronary atherosclerosis.</span> Recent research has shown its association with Coronary Artery Disease (CAD) prognosis. </span></span></p> <p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif"><strong>Objective:</strong> We propose to investigate whether CACS and EAT volume are associated in our population and, additionally, study the role of EAT volume alone in preventing overall major cardiovascular events (MACE) in a population free of cardiovascular disease.</span></span></p> <p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif"><strong>Methods:</strong> This prospective study included <span style="color:#010205">1024 participants (58.3±8.4 years; 75.6% male) from a Southern European population without apparent CAD</span> and followed during an extended period (average 6.1±4.8 years). All demographic, biochemical, CV risk factors and clinical data were performed. Non-contrast CT images obtained CACS and EAT, which was measured using a postprocessing workstation-the “TeraRecon Aquarius Workstation”. Data were displayed as mean and standard deviation (SD). Student’s t-test compared the numerical variables and Chi-square the categorical. Cox regression analysis, entering EAT volume, estimated variables independently associated with prognosis after adjustment to co-variates (age, gender, family history, alcohol, smoking, physical inactivity, body mass index, dyslipidemia and type 2 diabetes). Kaplan-Meier estimated the events-free survival. Statistical significance was defined as p<0.05, and all analyses were performed using SPSS statistical software version 25.0.</span></span></p> <p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif"><strong>Results:</strong> Increased EAT was associated with higher CAC score categories (p<0.0001). After Cox regression analysis, the increased EAT volume was associated with an adjusted hazard ratio of 1.95 (95% CI: 1.02-3.75; p=0.044). Higher EAT volumes presented worse survival free of events, when compared to lower EAT volumes.</span></span></p> <p><strong><span style="font-size:11.0pt"><span style="font-family:"Calibri",sans-serif">Conclusion:</span></span></strong><span style="font-size:11.0pt"><span style="font-family:"Calibri",sans-serif"> Our findings demonstrated that <span style="background-color:white"><span style="color:#1f1f1f">epicardial adipose tissue</span></span> and CAC score categories are correlated significantly. When used independently, EAT volume is a significant risk factor for MACES, and subjects with a high EAT volume had a worse vascular prognosis.</span></span></p>
Slides
Our mission: To reduce the burden of cardiovascular disease
Visit our site