Login
Search
Search
0 Dates
2025
2024
2023
2022
2021
2020
2019
2018
0 Events
CPC 2018
CPC 2019
Curso de Atualização em Medicina Cardiovascular 2019
Reunião Anual Conjunta dos Grupos de Estudo de Cirurgia Cardíaca, Doenças Valvulares e Ecocardiografia da SPC
CPC 2020
CPC 2021
CPC 2022
CPC 2023
CPC 2024
CPC 2025
0 Topics
A. Basics
B. Imaging
C. Arrhythmias and Device Therapy
D. Heart Failure
E. Coronary Artery Disease, Acute Coronary Syndromes, Acute Cardiac Care
F. Valvular, Myocardial, Pericardial, Pulmonary, Congenital Heart Disease
G. Aortic Disease, Peripheral Vascular Disease, Stroke
H. Interventional Cardiology and Cardiovascular Surgery
I. Hypertension
J. Preventive Cardiology
K. Cardiovascular Disease In Special Populations
L. Cardiovascular Pharmacology
M. Cardiovascular Nursing
N. E-Cardiology / Digital Health, Public Health, Health Economics, Research Methodology
O. Basic Science
P. Other
0 Themes
01. History of Cardiology
02. Clinical Skills
03. Imaging
04. Arrhythmias, General
05. Atrial Fibrillation
06. Supraventricular Tachycardia (non-AF)
07. Syncope and Bradycardia
08. Ventricular Arrhythmias and Sudden Cardiac Death (SCD)
09. Device Therapy
10. Chronic Heart Failure
11. Acute Heart Failure
12. Coronary Artery Disease (Chronic)
13. Acute Coronary Syndromes
14. Acute Cardiac Care
15. Valvular Heart Disease
16. Infective Endocarditis
17. Myocardial Disease
18. Pericardial Disease
19. Tumors of the Heart
20. Congenital Heart Disease and Pediatric Cardiology
21. Pulmonary Circulation, Pulmonary Embolism, Right Heart Failure
22. Aortic Disease
23. Peripheral Vascular and Cerebrovascular Disease
24. Stroke
25. Interventional Cardiology
26. Cardiovascular Surgery
27. Hypertension
28. Risk Factors and Prevention
29. Rehabilitation and Sports Cardiology
30. Cardiovascular Disease in Special Populations
31. Pharmacology and Pharmacotherapy
32. Cardiovascular Nursing
33. e-Cardiology / Digital Health
34. Public Health and Health Economics
35. Research Methodology
36. Basic Science
37. Miscellanea
0 Resources
Abstract
Slides
Vídeo
Report
CLEAR FILTERS
Characterisation of left atrial deformation during cardiovascular reverse remodelling induced by pregnancy and its potential predictors
Session:
SESSÃO DE COMUNICAÇÕES ORAIS 18 - IMAGEM AVANÇADA E BIOMARCADORES NA ESTRATIFICAÇÃO DE RISCO CARDIOVASCULAR: DA RESSONÂNCIA MAGNÉTICA DE PERFUSÃO À REMODELAGEM CARDÍACA
Speaker:
Ana Luísa dos Santos Barros
Congress:
CPC 2025
Topic:
K. Cardiovascular Disease In Special Populations
Theme:
30. Cardiovascular Disease in Special Populations
Subtheme:
30.7 Pregnancy and Cardiovascular Disease
Session Type:
Comunicações Orais
FP Number:
---
Authors:
Ana Barros; Ana Filipa Ferreira; Rui Alves; Juliana Morais; Débora Veiga; Maria João Azevedo; Carla Sousa; Ana Paula Machado; Adelino Leite-Moreira; Carla Ramalho; António S. Barros; Inês Falcão-Pires
Abstract
<p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif"><strong>Introduction: </strong>Haemodynamic overload during pregnancy leads to changes in the cardiovascular (CV) system, which may normalise within 6-12 months postpartum through a process called CV reverse remodelling (RR). Although cardiac systolic function is preserved during pregnancy and the postpartum period, impaired cardiac relaxation has been described during pregnancy and recovery after delivery. Left atrial (LA) strain has been named as a potential predictor of diastolic dysfunction; hence, it is relevant in this context.</span></span></p> <p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif"><strong>Purpose: </strong>To<strong> </strong>characterise LA strain during CV RR induced by pregnancy and identify its potential predictors.</span></span></p> <p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif"><strong>Methods: </strong>This prospective cohort study included volunteer pregnant women recruited from two tertiary healthcare centres between February 2019 and December 2023. Participants were evaluated by transthoracic echocardiography in the 3<sup>rd</sup> trimester [PT3, 30-35 weeks gestation, peak of CV remodelling] and in the 1<sup>st</sup>(PP1), 6<sup>th</sup>(PP2), and 12<sup>th</sup>(PP3) months postpartum, during CV RR. Generalised linear mixed-effect models were used to evaluate the CV RR, including the variation in LA strain and its potential predictors. </span></span></p> <p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif"><strong>Results: </strong>We included 169 women with a median age of 34 [31;37] years, having 35.5% at least one CV risk factor prior to pregnancy. After delivery, we observed a significant reduction in LA volume (49[42;56]mL/m<sup>2.7</sup> to 41[34;51]mL/m<sup>2.7</sup>, p<0.001) and E/e’ (6.67[5.44;7.96] to 5.79[4.87;6.54], p<0.001) as soon as 1 month postpartum. Regarding LA deformation, a significant reduction in LA strain was found from PT3 to PP1 (32[29;40]% to 29[26;34]%, p<0.001) and recovering in PP2 (32[29;40]% to 33[30;38]%, p=0.031). Although left ventricular (LV) systolic function was preserved during the follow-up period, a significant increase in global longitudinal strain (GLS, -21,6[-23,9;-20,1]% to -22,85[-24,4;-21,1]%, p=0.019) and ejection fraction (60[58; 63]% to 61[58;64]%, p=0.016) was observed from PT3 to PP2. In our cohort sample, LV GLS was an independent predictor of LA strain (-0.53[-0.74,-0.32], p<0.001). The presence of CV risk factors (0.03[-1.65,1.70], p=0.974), pregnancy complications (-0.43[-2.14;1.29], p=0.6624), LA volume (-0.10[-0.34,0.13], p=0.399), E/e’ (0.05[-0.42,0.52], p=0.830), and age (-0.04[-0.21,0.13], p=0.632) showed no significant impact on LA strain.</span></span></p> <p style="text-align:justify"><span style="font-size:11pt"><span style="font-family:Calibri,sans-serif"><strong>Conclusion: </strong>Although LA volume and E/e' demonstrated recovery at 1 month postpartum, LA deformation exhibited significant improvement only after 6 months. LV GLS was identified as an independent predictor of LA strain.</span></span></p>
Our mission: To reduce the burden of cardiovascular disease
Visit our site